Pharmacological Tie2 activation in kidney transplantation

Figure 3 Vasculotide treatment reduces vascular inflammation and tissue infiltration in kidney transplantation. Fluorescent immunohistochemistry for (A) ICAM-1 (red), (B) Gr-1 (red) and (C) F4/80 (red) in kidney cross-sections of transplanted mice (vehicle or VT-treated) on day 28 after transplantation. Autofluorescence is shown in green. Images are exemplary for n = 5/condition; D: Immunoblot of murine kidney homogenate for ICAM-1 and GAPDH for the same conditions. VT: Vasculotide; ICAM-1: Intercellular adhesion molecule; GAPDH: Glyceraldehyde 3-phosphate dehydrogenase.