BK nephropathy in the native kidneys of patients with organ transplants: Clinical spectrum of BK infection

Table 2 BK nephropathy in recipients of bone marrow or stem cell transplants

Ref.	Gender age	Renal function	Clinical associations
[8]	Female 36 yr	ESRD Dialysis	Relapsed Hodgkin’s lymphoma
[8]	Female 43 yr	ESRD Dialysis	Acute myelogenous leukemia
[11]	Male 47 yr	ESRD Dialysis	Non-Hodgkin’s lymphoma
[49]	Male 17 yr	ESRD Dialysis	Myelodysplastic syndrome Severe hemorrhagic cystitis No renal biopsy Death from multi-organ failure
[50]	Female 28 yr	ESRD Dialysis	Acute myelogenous leukemia Recurrent CMV reactivation
[51]	NR NR	ARF	Underlying disease NR Adenovirus pneumonia Adenovirus nephritis Death
[58]	Male 14 yr	Rising SCr	Acute myelogenous leukemia Death from multi-organ failure
[60]	Male 10 yr	GFR normalized	Acute myelogenous leukemia No renal biopsy
[63]	Male 51 yr	ESRD Dialysis	Myelodysplastic syndrome Hepatorenal syndrome GVHD Death from Pseudomonas sepsis
[64]	Male 10 yr	Peak SCr 3.5 mg/dL Scr at 1.7 mg/dL post-treatment	Chronic myelogenous leukemia Adenovirus and bacterial infections Severe GVHD
[64]	Male 13 yr	ESRD Declined dialysis	Fanconi’s anemia Gram-positive bacteremias Pulmonary aspergillosis Hyperacute GVHD Death
[70]	Female 10 yr	ESRD Dialysis	Recurrent metastatic neuroendocrine tumor Thrombocytopenia, leukopenia, lymphopenia Antineutrophil-antiplatelet antibodies Death from sepsis
[75]	Female 10 yr	Peak SCr 1.58 mg/dL SCr at 1.1-1.4 mg/dL post-treatment	Myelodysplastic syndrome Acute GVHD
[77]	Male 59 yr	CKD stage 5 not requiring dialysis	Myelodysplastic syndrome
[79]	Male 58 yr	Death due to sepsis eGFR stable at 20 at the time of death	Large B cell lymphoma Acute GVHD

BK nephropathy was manifested at various times post-heart transplantation. Ages reported in this Table are the calculated ages at the time of diagnosis of BK nephropathy. ESRD: End-stage renal disease; ARF: Acute renal failure; SCr: Serum creatinine; GFR: Glomerular filtration rate; GVHD: Graft vs host disease; NR: Not report.