Liver transplantation and the management of progressive familial intrahepatic cholestasis in children

Figure 4 Progressive familial intrahepatic cholestasis type 1 and 2 can also present with duct paucity. A and B: The portal tracts show an absence of bile duct with periportal duct reaction; B: A higher power view of the portal tract with vein on the left artery on the right (arrow) and no appreciable bile duct. Keratin 7 is negative in this portal tract in B and positive in the bile duct reaction (arrow) with some bile duct progenitor cells (paler brown staining arrowhead).