Liver transplantation for hepatocellular carcinoma in Ireland: Pre-operative alpha-fetoprotein predicts tumour recurrence in a 14-year single-centre national experience

Table 2 Univariate analysis of factors affecting overall survival

	HR	CI	P-value
Male sex	0.786	0.301-2.055	0.623
Age	1.001	0.954-1.051	0.952
Aetiology of HCC
Alcoholic liver disease	0.523	0.175-1.567	0.247
Hepatitis C	2.098	0.849-5.183	0.108
Haemochromatosis	0.715	0.239-2.143	0.549
Other	1.198	0.459-3.126	0.712
Pre-operative α-fetoprotein > 100 ng/mL	1.502	0.437-5.165	0.519
Compliant with Milan criteria	0.994	0.381-2.590	0.989
Compliant with UCSF criteria	0.871	0.290-2.618	0.805
Largest lesion	1.207	0.963-1.513	0.102
Cirrhosis	23.309	0.024-224.813	0.369
Steatosis	0.044	0.000-187.285	0.465
Multi-focal lesions	1.201	0.499-2.890	0.683
Micro-vascular invasion	1.489	0.619-3.578	0.374
Tumour differentiation
Well	0.862	0.349-2.131	0.748
Moderate	1.100	0.448-2.698	0.835
Poor	1.159	0.268-5.022	0.843
Incidental lesions	0.450	0.060-3.391	0.438

HCC: Hepatocellular carcinoma; UCSF: University of California San Francisco.