Copyright
©The Author(s) 2016.
World J Transplant. Mar 24, 2016; 6(1): 144-154
Published online Mar 24, 2016. doi: 10.5500/wjt.v6.i1.144
Published online Mar 24, 2016. doi: 10.5500/wjt.v6.i1.144
Table 2 Equivalence comparison of pharmacokinetic parameters after conversion tacrolimus-BID to extended release tacrolimus[19]
| PK parameter | Extended release tacrolimus (n = 60) | Tacrolimus-BID (n = 60) | Ratio (90%CI) extended release tacrolimus: Tacrolimus-BID |
| AUC0-24 (ng・h/mL) | 217.75 | 234.42 | 92.9% (89.9-96.0) |
| Cmax (ng/mL) | 15.99 | 21.84 | 73.2% (67.7-78.7) |
| Cmin (ng/mL) | 6.60 | 7.26 | 90.9% (87.3-94.6) |
- Citation: Patel N, Cook A, Greenhalgh E, Rech MA, Rusinak J, Heinrich L. Overview of extended release tacrolimus in solid organ transplantation. World J Transplant 2016; 6(1): 144-154
- URL: https://www.wjgnet.com/2220-3230/full/v6/i1/144.htm
- DOI: https://dx.doi.org/10.5500/wjt.v6.i1.144