Copyright
©The Author(s) 2016.
World J Transplant. Mar 24, 2016; 6(1): 135-143
Published online Mar 24, 2016. doi: 10.5500/wjt.v6.i1.135
Published online Mar 24, 2016. doi: 10.5500/wjt.v6.i1.135
Table 1 Post-transplant complications among obese vs nonobese patients
Ref. | Groups | Complication | Outcome differences | ||
Obese | Nonobese | Obese | Nonobese | ||
Singh et al[9] | BMI > 30 (34.1 ± 3.68) | BMI ≤ 30 (23.6 ± 3.18) | OR time (min) | 155 ± 59 | 119 ± 44 |
1999-2002 | n = 33 | n = 35 | LOS (d) | 13.7 ± 10 | 9.48 ± 4.8 (P = 0.029) |
Age 48 ± 11.1 | Age 43.5 ± 13.5 | DGF | 33.3% | 17.1% (P = 0.12) | |
Wound infection | 18.2% | 0 (P = 0.01) | |||
Lymphocele | 18.2% | 2.94% (P = 0.02) | |||
Perinephric HTMA | 12.1% | 0 (P = 0.05) | |||
Incisional hernia | 6% | 3.7% (P = 0.68) | |||
NODAT | 9% | 3.7% (P = 0.41) | |||
Cacciola et al[10] | BMI ≥ 35 | BMI 30-34.9 | 1/5 yr graft surv | 75%/63% | 98.9/94.5 (P = NS) |
1993-2003 | n = 24 (Group B) | n = 90 (Group A) | 1/5 yr pt surv | 87.5/79.2 | 98.9/95.6 (P = NS) |
Age 45 (20-61) | Age 45 (25-70) | DGF | 16.5% | 22% (P = NS) | |
Mehta et al[11] | BMI ≥ 30 | BMI < 30 | 1 yr graft surv | 94% | 97% (P = 0.51) |
1999-2002 | n = 16 | n = 37 | 1 yr patient surv | 100% | 100% |
Living donor | Age 50 ± 16 | Age 43 ± 16 | Acute rejection | 19% | 8% (P = 0.35) |
Wound Cxn | 19% | 13.5% (P = 0.68) | |||
Other Cxns | 25% | 11% (P = 0.22) | |||
DGF | 19% | 2.7% (P = 0.077) | |||
LOS (d) | 8.4 ± 7 | 6.4 ± 5 (P = 0.68) | |||
Marks et al[12] | BMI ≥ 35 (35-56) | BMI ≤ 25 (17-28) | 1/3 yr graft surv | LD 100/100 DD 92/75 | LD 95/91 DD 94/90 |
1995-2000 | n = 23 | (n = 224) | 1/3 yr pt surv | LD 100/100 DD 92/83 | LD 97/95 DD 96/94 |
Age DD: 44 ± 14 | Age DD: 48.5 ± 13 | LOS (d) | LD 10.2 ± 8.0 DD 12.9 ± 9.0 | LD 6.0 ± 4.1 DD 7.8 ± 3.0 | |
Age LD: 46 ± 1 | Age LD: 43 ± 13 | Readmission 6 mo | LD 82% DD 92% | LD 20% DD 49% | |
Mult admits 1st 6 mo | LD 44% DD 50% | LD 21% DD 18% | |||
Major wound infxn | LD 44% DD 33% | LD 2% DD 4% | |||
Grosso et al[13] | BMI > 30 | BMI ≤ 30 | Graft loss 1 yr/3 yr | 6.4/42.9 | 5.3/7.7 |
2000-2010 | n = 64 | n = 312 | Pt death 1 yr/3 yr | 7.6/46.2 | 3.5/11.8 |
Age 49.1 ± 12.9 | Age 49.8 ± 11.1 | DGF | 31.3% | 20.5% (P = 0.253) | |
(BMI 25-30) | |||||
Age 44.9 ± 13.7 | |||||
(BMI < 25) | |||||
Schwarznau et al[14] | BMI > 25 (28.1 ± 2.6) | BMI < 25 (21.4 ± 2.0) | 1 yr graft survival | 94.6% | 76% (P < 0.001) |
2000-2004 | n = 25 | n = 56 | |||
Living donor | Age 49.2 ± 10.9 | Age 42.8 ± 13.6 | |||
Bardonnaud et al[15] | BMI ≥ 30 (35.1 ± 4.35) | BMI < 30 (22.9 ± 3.17) | DGF | 38% ± 0.5% | 14% ± 0.34% (P = 0.004) |
2004-2008 | n = 21 | n = 179 | Lymphocele | 14.3% | 4.5 (P = 0.062) |
Age 53.3 ± 11.19 | Age 46.7 ± 15.05 | Wound dehiscence | 4.8% ± 0.22% | 2.2% ± 0.15% (P = 0.485) | |
(pretransplant DM) | 29% | 6% (P < 0.0001) | |||
LOS (d) | 24.9 | 15.6 (P = 0.008) | |||
Gusukuma et al[16] | BMI ≥ 35 (36.8 ± 1.7) | BMI < 30 (22.6 ± 3.3) | 1 yr graft/pt surv | 93.6%/95.6% | 97.7%/98.1% (P = NS) |
1998-2008 | n = 47 | n = 2822 | 5 yr graft/pt surv | 84.0%/89.1% | 88.8%/90.5% (P = NS) |
Age 46.5 ± 10.9 | Age 40.7 ± 12.1 | DGF | 16.7% ± 19.3% | 13.5% ± 16.2% (P = NS) | |
Wound dehiscence | 19.1% | 1.9% (P < 0.001) | |||
Lymphocele | 6.4% | 2.6% (P = 0.054) | |||
NODAT | 36% | 16.2% (P < 0.001) | |||
LOS (d) | 15.9 ± 16.7 | 11.3 ± 11.4 (P < 0.001) | |||
Furriel et al[17] | BMI ≥ 30 (32.44 ± 1.86) | BMI < 25 (22.03 ± 1.79) | DGF | 26.9% | 16.9% |
1984-2008 | n = 26 | n = 295 | Lymphocele | 7.7% | 1.4% |
Age 46.08 ± 12.75 | Age 41.51 ± 13.23 | Wound dehiscence | 11.5% | 0.7% | |
Behzadi et al[18] | BMI ≥ 30 (none > 35) | BMI < 30 | RAS | 17.6% | 2.8% (P < 001) |
2006-2008 | n = 34 | n = 146 | Hematoma | 47.9% | 17.6% (P = 0.009) |
Age 39.8 | Wound Cxn | 64.7% | 9.6% (P < 0.001) | ||
Renal vein thromb | 2% | 0% (P < 0.05) | |||
DGF | 8.8% | 6.80% | |||
Lymphocele | 2.9% | 1.40% | |||
Johnson et al[19] | BMI ≥ 30 (32.0 ± 0.3) | BMI < 30 (23.4 ± 0.2) | Wound breakdown | 14% | 4% (P < 0.01) |
1994-2000 | n = 59 | n = 434 | Wound dehiscence | 3% | 0% (P < 0.01) |
Wound Infection | 15% | 8% (P = 0.11) |
- Citation: Tran MH, Foster CE, Kalantar-Zadeh K, Ichii H. Kidney transplantation in obese patients. World J Transplant 2016; 6(1): 135-143
- URL: https://www.wjgnet.com/2220-3230/full/v6/i1/135.htm
- DOI: https://dx.doi.org/10.5500/wjt.v6.i1.135