Perioperative effects of high doses of intraoperative thymoglobulin induction in liver transplantation

Table 2 Intraoperative parameters concerning transfusions, acid-base balance, fluids (colloids and crystalloids) and vasopressors administered in the two study groups

Intraoperative parameters recorded	ATG group	Control group	P
No. of patients transfused with RBC	16 (100%)	7 (43.8%)	0.01
Intraoperative blood loss (mL)	3953 ± 3126	1419 ± 940	0.05
Omologous blood transfused (mL)	2092 ± 1856	472 ± 632	0.02
Crystalloids (mL)	11356 ± 4419	6771 ± 2416	0.008
PLT transfused (g)	374 ± 537	15.6 ± 62.5	0.017
FFP transfused (g)	671 ± 1125	143 ± 349	0.015
No. of patients transfused with PLT	8 (50%)	1 (6.2%)	0.015
No. of patients transfused with FFP	9 (56.2%)	3 (18.8%)	0.07
No. of patients with core temperature > 37 °C	8 (50%)	1 (6.2%)	0.015
No. of patients who received Noradrenaline before reperfusion	11 (68.8%)	3 (18.8%)	0.013
Mean dosage of noradrenaline infused before reperfusion (μg/kg per minute)	0.08 ± 0.07	0.01 ± 0.38	0.03
Mean dosage of noradrenaline infused after reperfusion (μg/kg per minute)	0.2 ± 0.07	0.10 ± 0.11	0.029
No. of patients who received noradrenaline before and after reperfusion	11 (68.8%)	3 (18.8%)	0.013
Mean dosage of adrenaline infused at reperfusion (g)	106 ± 86	28 ± 21	0.047
pH before reperfusion	7.29 ± 0.85	7.36 ± 0.5	0.01
BE before reperfusion	-7.74 ± 4	-4.7 ± 2.6	0.005
pH after reperfusion	7.24 ± 0.7	7.3 ± 0.5	0.03
BE after reperfusion	-8.7 ± 3.2	-6.5 ± 2.4	0.02

Only statistically significant data are expressed. RBC: Red blood cell; FFP: Fresh frozen plasma; PLT: Platelets; BE: Base excess; ATG: Antithymocyte globulin.