Clinical and pathological features of kidney transplant patients with concurrent polyomavirus nephropathy and rejection-associated endarteritis

Table 1 Patient demographics

	Known prior change of IS (n = 4)	No known prior change of IS (n = 3)	All cases (n = 7)
Age, years (range)	55.5 (43-68)	38.7 (15-58)	48.3 (15-68)
Sex, n
Male	4	3	7
Female	0	0	0
Cause of end stage renal disease, n
DM ± HTN	4	1	5
PCKD	0	1	1
CON	0	1	1
No. of HLA matches, average (range)
Class I (HLA-A, HLA-B)	0.25 (0-1)	0	0.14 (0-1)
Class II (HLA-DR)	0.50 (0-2)	0.33 (0-1)	0.43 (0-2)
Donor age, years (range)	38.5 (17-57)	22.0 (18-30)	31.4 (17-57)
Cold ischemia time, hours (range)	22.4 (15.0-37.5)	17.8 (14.1-21.2)	20.4 (14.1-37.5)
Delayed graft function, n	1	0	1
Baseline creatinine, mg/dL (range)	1.4 (1.1-1.8)	1.6 (1.2-1.8)	1.4 (1.1-1.8)
Time of index biopsy, months after	231 (135-317)	507 (45-1293)	349 (45-1293)
transplant (range)
Creatinine at index biopsy, mg/dL	3.3 (1.8-6.2)	1.9 (1.7-2.2)	2.7 (1.7-6.2)
(range)
Donor-specific antibodies prior to	0	0	0
transplant

HLA: Human leukocyte antigen; DM: Diabetes mellitus; HTN: Hypertension; PCKD: Polycystic kidney disease; CON: Congenital obstructive nephropathy; IS: Immunosuppression.