Copyright
©The Author(s) 2015.
World J Transplant. Dec 24, 2015; 5(4): 267-275
Published online Dec 24, 2015. doi: 10.5500/wjt.v5.i4.267
Published online Dec 24, 2015. doi: 10.5500/wjt.v5.i4.267
Characteristic | Microparticles |
Size | 100-1000 nm |
Mechanism of formation | Outward blebbing of plasma membrane |
How detected | Flow cytometry, capture-based assays and electron microscopy |
Characteristic features | Annexin V-positivity and presence of cell-specific surface markers |
Composition | Protein, RNA and miRNA |
Membrane properties | Externalized phosphatidylserine, rich in lipid rafts and impermeable |
Name of antigens | CD31 (PECAM-1) |
CD51 (vitronectin receptor, αv β3) | |
CD105 (endoglin) | |
CD144 (VE-cadherin) | |
CD146 (S-Endo 1-associated antigen) |
- Citation: Dursun I, Yel S, Unsur E. Dynamics of circulating microparticles in chronic kidney disease and transplantation: Is it really reliable marker? World J Transplant 2015; 5(4): 267-275
- URL: https://www.wjgnet.com/2220-3230/full/v5/i4/267.htm
- DOI: https://dx.doi.org/10.5500/wjt.v5.i4.267