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Copyright ©The Author(s) 2015.
World J Transplant. Dec 24, 2015; 5(4): 267-275
Published online Dec 24, 2015. doi: 10.5500/wjt.v5.i4.267
Table 1 Characteristics of endothelial microparticles[9]
CharacteristicMicroparticles
Size100-1000 nm
Mechanism of formationOutward blebbing of plasma membrane
How detectedFlow cytometry, capture-based assays and electron microscopy
Characteristic featuresAnnexin V-positivity and presence of cell-specific surface markers
CompositionProtein, RNA and miRNA
Membrane propertiesExternalized phosphatidylserine, rich in lipid rafts and impermeable
Name of antigensCD31 (PECAM-1)
CD51 (vitronectin receptor, αv β3)
CD105 (endoglin)
CD144 (VE-cadherin)
CD146 (S-Endo 1-associated antigen)