Copyright
©The Author(s) 2015.
World J Transplant. Mar 24, 2015; 5(1): 1-10
Published online Mar 24, 2015. doi: 10.5500/wjt.v5.i1.1
Published online Mar 24, 2015. doi: 10.5500/wjt.v5.i1.1
Table 1 Oxygen tension of alternative transplant sites and the ability to support islet transplantation
| Site | Oxygen tension of native tissue (mmHg) | Oxygen tension of transplanted islets (mmHg) | Percent to pancreas | Vascular density of transplanted islets (vessel/mm2) (perfusion rate) | Ref. |
| Pancreas | Approximately 40 | n/a | n/a | 1074 ± 174 (6-7 mL/min per gram) | [44-46,61,75] |
| Portal vein | Approximately 40 | Approximately 5 | 12.50% | < 100 TPU | |
| Spleen | No data | Approximately 5 | CBD | > 100 TPU | |
| Kidney capsule | 15 | Approximately 5 | 12.50% | > 100 TPU | |
| Peritoneal lining | Approximately 50 | No data | CBD | No data | [76] |
| Intramuscular space | 15 | 25 | 63% | 1162 ± 120 | [77,78] |
| Subcutaneous site | 8 | No data | CBD | No data | [79] |
- Citation: Moore SJ, Gala-Lopez BL, Pepper AR, Pawlick RL, Shapiro AJ. Bioengineered stem cells as an alternative for islet cell transplantation. World J Transplant 2015; 5(1): 1-10
- URL: https://www.wjgnet.com/2220-3230/full/v5/i1/1.htm
- DOI: https://dx.doi.org/10.5500/wjt.v5.i1.1