1400W reduces ischemia reperfusion injury in an ex-vivo porcine model of the donation after circulatory death kidney donor

doi:10.5500/wjt.v4.i4.299

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Dec 24, 2014 (publication date) through Nov 24, 2024

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transplant. Dec 24, 2014; 4(4): 299-305
Published online Dec 24, 2014. doi: 10.5500/wjt.v4.i4.299

Table 2 Histology score

	Control		1400W
	Pre	Post	Pre	Post
Tubular dilatation	0.91 ± 0.68	1.60 ± 0.60^a	2.03 ± 0.80^b	1.63 ± 0.81
Tubular debris	1.44 ± 0.50	1.14 ± 0.73	1.47 ± 0.50	2.07 ± 0.74^a^b
Vacuolation	0.52 ± 0.76	1.09 ± 1.091	0.50 ± 0.60	1.00 ± 0.91^a
Interstitial oedema	1.33 ± 0.48^b	1.29 ± 0.52	0.93 ± 0.70	1.47 ± 0.82^a

Pre and post reperfusion biopsies in the control and 1400W groups. Biopsies were scored over 5 fields assessing tubular dilatation, tubular debris, vacuolation and interstitial oedema.

^aP≤ 0.05 between time points,

^bP≤ 0.05 between groups. Mann Whitney U-test.

Citation: Hosgood SA, Yates PJ, Nicholson ML. 1400W reduces ischemia reperfusion injury in an ex-vivo porcine model of the donation after circulatory death kidney donor. World J Transplant 2014; 4(4): 299-305
URL: https://www.wjgnet.com/2220-3230/full/v4/i4/299.htm
DOI: https://dx.doi.org/10.5500/wjt.v4.i4.299