Transplant options for patients with type 2 diabetes and chronic kidney disease

Table 1 Selected data from pancreas transplantation single-center and database studies in type 2 diabetes mellitus patients

Ref.	PTx Era	Numberof PTx (n)	Age at PTx(yr)	BMI (kg/m2)	Follow-up (yr)	Pancreas survival rates (yr)	Patient survival rates(yr)
Light et al[37]	1989-1999	30 SPK	40 ± 9.31 41.7 ± 6.62	24.8 ± 5.41 25.5 ± 42	3.8	82% (1)1 95% (1)2	82% (1)1 100% (1)2
						82% (5) 95% (5)	82% (5) 95% (5)
Light et al[38]	1989-2004	38 SPK	40 ± 9.31 37.9 ± 8.72	24.8 ± 5.41 23 ± 4.52	> 10	67% (5)1 56% (10)2	73% (5)1 70% (10)2
Light et al[20]	1989-2008	58 SPK	42.8 ± 8.4	26.1 ± 4.4	> 15-20	58.60% (> 10)	75.8% (> 10)
Nath et al[39]	1994-2002	7 SPK 4 PAK 6 PTA	52.5 ± 8.4	27.2 ± 5	4.3	65% (3.3)	94% (1) 71% (3.3)
Singh et al[40]	2002-2007	7 SPK	51 ± 2.9	ND	3.3	71% (3.3)	86% (1) 71% (3.3)
Chakkera et al[41]	2003-2008	10 SPK	51.9 ± 9	27 ± 3	1.3	100% (1)	100% (1)
Margreiter et al[21]	2000-2009	21 SPK	53.6 ± 5.9	25.1 ± 3.3	7.3 ± 3	81.8 (1) 75.9 (5)	90.5 (1) 80.1 (5)
Sampaio et al[14]	2000-2007	582 SPK	47 (40-52)	< 18.5 = 2.8% 18.5 to 25 = 43.9% 25 to 30 = 36.2% > 30 = 17.15	3.7	-	67% (5)
Wiseman et al[19]	2000-2008	424 SPK	18-34 = 6.1% 35-49 = 54% 50-59 = 39.9%	24.7 ± 2.8	5	87.7 (1) 83.6 (5)	82% (5)

¹Data for non African-Americans;

²Data for African-Americans. PTx: Pancreas transplantation; PAK: Pancreas after kidney; PTA: Pancreas transplant alone; SPK: Simultaneous pancreas kidney.