Optimal stem cell source for allogeneic stem cell transplantation for hematological malignancies

Figure 1 Suggested algorithm for selection of donor and source of stem cells for patients with hematological malignancies. ¹Need to consider pros and cons of BM and PBSC in the context of donor preference, risk of relapse, conditioning regimen, graft-versus-host disease prophylaxis, and graft manipulations, etc. PBSC: Peripheral blood stem cell; HSCT: Hematopoietic stem cell transplant; HLA: Human leukocyte antigen; BM: Bone marrow.