New developments in transplant-acquired allergies

doi:10.5500/wjt.v3.i3.30

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Sep 24, 2013 (publication date) through Feb 6, 2025

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transplant. Sep 24, 2013; 3(3): 30-35
Published online Sep 24, 2013. doi: 10.5500/wjt.v3.i3.30

Table 2 Side effects of immunosuppressive agents help developing transplant-acquired allergies in solid organ recipients

Types of side effects	Immunosuppressive agents
	Tacrolimus	Cyclosporine A
Intestinal injury	+	-
Inhibition of cellular energy production in intestine	+	-
Th1/Th2 imbalance	++	+
IL-2 production	↓↓	↓
IL-5 production	↑↑	↑
IL-10 production	↑↑	↑
IL-13 production	↑↑	↑
IgE production	↑↑	↑
Immunosuppression	++	+

IgE: Immunoglobulin E; IL: Interleukin; Th: T-helper cells; -: No effect; +: Positive effect; ++: Strong positive effect; ↓: Decrease; ↑: Increase; ↓↓: Strong decrease; ↑↑: Strong increase.

Citation: Özdemir &. New developments in transplant-acquired allergies. World J Transplant 2013; 3(3): 30-35
URL: https://www.wjgnet.com/2220-3230/full/v3/i3/30.htm
DOI: https://dx.doi.org/10.5500/wjt.v3.i3.30