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World J Transplant. Jun 24, 2013; 3(2): 7-25
Published online Jun 24, 2013. doi: 10.5500/wjt.v3.i2.7
Published online Jun 24, 2013. doi: 10.5500/wjt.v3.i2.7
Table 7 Selected randomized trials on calcineurin inhibitors avoidance
| Study (yr) | Intervention arm | Control arm | Study length (mo) |
| Flechner (2004) | IL2Ri+ SRLcc + MMF + S (n = 31) | IL2Ri + CsA + MMF + S (n = 30) | 24 |
| Flechner (2007) | IL2Ri +SRLcc + MMF+S (n = 31) | IL2Ri + CsA + MMF + S (n = 30) | 60 |
| Larson (2006) | rATG + SRL + MMF + S (n = 81) | rATG + TAC + MMF + S (n = 84) | 12 |
| SYMPHONY (2007) | IL2Ri + low SRL + MMF + S (n = 399) | IL2Ri+sCsA+MMF+S (n = 390) | 36 |
| Hamdy (2008) | IL2Ri + SRL+ MMF+S (n = 67) | IL2Ri + lowTAC+ SRL+S (n = 65) | 60 |
| Lo (2004) | rATG+SRL+MMF+S (n = 41) | rATG+TAC+MMF+S (n = 29) | 12 |
| Ruggenenti (2007) | Alem+SRL+MMF+ S (n = 11) | Alem+ CsA+MMF+S (n = 10) | 24 |
| Spiesser group (2007) | rATG +SRL + MMF + S (n = 71) | rATG + CsA +MMF+S (n = 74) | 12 |
| Glotz (2010 ) | rATG + SRL+ MMF + S (n = 71) | rATG+ TAC+ MMF+ S (n = 70) | 12 |
| ORION (2011) | IL-2Ri + SRL + MMF+S (n = 155) | IL-2Ri + TAC + MMF + S (n = 140) | 24 |
- Citation: Salvadori M, Bertoni E. Is it time to give up with calcineurin inhibitors in kidney transplantation? World J Transplant 2013; 3(2): 7-25
- URL: https://www.wjgnet.com/2220-3230/full/v3/i2/7.htm
- DOI: https://dx.doi.org/10.5500/wjt.v3.i2.7