Is it time to give up with calcineurin inhibitors in kidney transplantation?

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Jun 24, 2013 (publication date) through Dec 4, 2024

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transplant. Jun 24, 2013; 3(2): 7-25
Published online Jun 24, 2013. doi: 10.5500/wjt.v3.i2.7

Table 5 Glomerular filtration rate gain in different minimization trials

Study	Calcineurin inhibitors	Length	Glomerular filtration rate gain (mL/min)
US09	TAC	6 mo	+2.8
De Sevaux	CsA	6 mo	+4.0
CAESAR Study	CsA	12 mo	+2.3
SYMPHONY Study	TAC vs CsA	3 yr	+4.6
A2309	CsA	12 mo	+1.9
ASSET Study	TAC	12 mo	+5.3
B156	CsA	3 yr	+4.9
EVEREST	CsA	6 mo	+2.1

CsA: Cyclosporine; TAC: Tacrolimus.

Citation: Salvadori M, Bertoni E. Is it time to give up with calcineurin inhibitors in kidney transplantation? World J Transplant 2013; 3(2): 7-25
URL: https://www.wjgnet.com/2220-3230/full/v3/i2/7.htm
DOI: https://dx.doi.org/10.5500/wjt.v3.i2.7