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World J Transplant. Jun 24, 2013; 3(2): 7-25
Published online Jun 24, 2013. doi: 10.5500/wjt.v3.i2.7
Published online Jun 24, 2013. doi: 10.5500/wjt.v3.i2.7
Table 1 Withdrawal/conversion study
| Study (yr) | Intervention arm | Control arm | CNI sparing strategy | Study length (mo) |
| RMR (2004) | SRL, Steroids, CsA→Withdrawal by 3 mo (n = 215) | SRL, Steroids, CsA (n = 215) | Withdrawal by 3 mo | 48 |
| Spare the Nephron (2011) | MMF, S, CNI→SRL (30-180 d) (n = 148) | MMF, S, CNI (n = 151) | Conversion by 30-180 d | 24 |
| CONCEPT (2009) | MMF, S, CsA→SRL by 3 mo (n = 95) | MMF, S, CsA (n = 97) | Conversion by 3 mo | 12 |
| SMART (2010) | MMF, S, CsA→SRL 10-24 d (n = 70) | MMF, S, CsA (n = 71) | Conversion by 10-24 d | 12 |
| ZEUS (2012) | EC-MPS, S, CsA→EVR by 4.5 d (n = 154) | EC-MPS, S, CsA (n = 146) | Conversion by 4.5 mo | 36 |
| HERAKLES (2012) | EC-MPS, S, CsA→EVR by 3 mo (n = 171) | EC-MPS, S, CsA (n = 166) | Conversion by 3 mo | 12 |
- Citation: Salvadori M, Bertoni E. Is it time to give up with calcineurin inhibitors in kidney transplantation? World J Transplant 2013; 3(2): 7-25
- URL: https://www.wjgnet.com/2220-3230/full/v3/i2/7.htm
- DOI: https://dx.doi.org/10.5500/wjt.v3.i2.7