Review
Copyright ©2012 Baishideng.
World J Transplant. Dec 24, 2012; 2(6): 84-94
Published online Dec 24, 2012. doi: 10.5500/wjt.v2.i6.84
Table 4 Recommended treatment of polyomavirus-associated nephropathy by reduction or switching of immunosuppression[49]
SwitchingDecreasing
Tacrolimus → Cyclosporine A (trough levels 100-150 ng/mL)Tacrolimus (trough levels < 6 ng/mL)
Mycophenolate mofetil → Azathioprine (dose ≤ 100 mg/d)Cyclosporine A (trough levels 100-150 ng/mL)
Tacrolimus → sirolimus (trough levels < 6 ng/mL)Mycophenolate mofetil dose ≤ 1 g/d
Mycophenolate mofetil → sirolimus (trough levels < 6 ng/mL)Cyclosporine A (trough levels 100-150 ng/mL)
Mycophenolate mofetil → leflunomide