Current state of renal transplant immunosuppression: Present and future

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Aug 24, 2012 (publication date) through Nov 27, 2024

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World Journal of Transplantation

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2220-3230

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Transplant. Aug 24, 2012; 2(4): 51-68
Published online Aug 24, 2012. doi: 10.5500/wjt.v2.i4.51

Table 4 Comparative adverse effects of prolonged release Tacrolimus and Tacrolimus (%)

ADR	Prolonged released Tacrolimus	Tacrolimus twice daily
Gastrointestinal
Diarrhea	45.3	44.3
Loose stools	5.1	7.1
Metabolism and nutritional
Hyperlipidemia	16.4	17.5
Diabetes mellitus	14.0	11.3
Hyponatremia	2.8	0.9
Infections and infestations
Sinusitis	7.0	3.3
Gastroenteritis	6.5	0.5
Peripheral edema	35.5	34.9
Nervous system
Tremor	35.0	34.4
Paraesthesia	5.6	1.4
Vascular
Orthostatasis	7.0	4.7
Lymphocele	0.5	0.9
Psychiatric
Insomnia	25.7	30.2
Skin
Alopecia	6.5	7.1

Citation: Kalluri HV, Hardinger KL. Current state of renal transplant immunosuppression: Present and future. World J Transplant 2012; 2(4): 51-68
URL: https://www.wjgnet.com/2220-3230/full/v2/i4/51.htm
DOI: https://dx.doi.org/10.5500/wjt.v2.i4.51