Optimizing liver utilization for transplantation with partial grafts undergoing normothermic machine perfusion: Two case reports

Figure 3 Sequence of the logistic steps for procurement and connection to normothermic machine perfusion pump of deceased donor partial grafts. A: Logistic scenarios that lead to normothermic machine perfusion (NMP) of just one of the partial grafts; B: Logistic scenarios that lead to NMP of both partial grafts. In situ normothermia times are largely non-modifiable. Cold ischemia times should be kept minimal. Ex situ normothermia times are modifiable and can be extended ad lib to optimize logistics. Completion split in B2 scenario usually requires additional benching for at least one of the partial grafts; C: For comparison purposes, it describes current practices without NMP. In situ normothermia is depicted with orange. Standard cold storage conditions are depicted in blue. Ex situ normothermia is depicted in red. NMP: Normothermic machine perfusion; OLTx: Orthotopic liver transplantation.