Increased reflux burden on pre-transplant reflux testing independently predicts significant pulmonary function decline after lung transplantation

Figure 1 Kaplan-Meier analysis of time to pulmonary decline by pre-transplant. A: Kaplan-Meier analysis of time to pulmonary decline by pre-transplant acid exposure time. Increased acid exposure time (> 4.2% of time with pH < 4) resulted in earlier development of forced expiratory volume in 1 decline in transplant recipients. These results were preserved on multivariate analysis when controlling for body-mass index and gender; B: Kaplan-Meier analysis of time to pulmonary decline by pre-transplant proximal acid reflux episodes. Increased proximal episodes > 28 resulted in earlier development of forced expiratory volume in 1 decline in transplant recipients on univariate analysis.