Upper limit of normothermic machine preservation of liver grafts from donation after circulatory death yet to be defined

Figure 1 Definitions of procurement and preservation time intervals in relationship with donation surgical steps (depicted in green). “Cold” denotes that while on normothermic machine perfusion pump, graft is maintained at normothermia, foregoing prolonged period of cold ischemia time; “rewarming” denotes that graft is not maintained on ice so does not undergo period of true rewarming. AT: Air temperature; CIT: Cold ischemia time; SBP: Systolic blood pressure; WI: Warm ischemia; WIT: Warm ischemia time.