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©The Author(s) 2025.
World J Transplant. Jun 18, 2025; 15(2): 101517
Published online Jun 18, 2025. doi: 10.5500/wjt.v15.i2.101517
Published online Jun 18, 2025. doi: 10.5500/wjt.v15.i2.101517
Table 2 Kidney biopsy findings, n (%)
| Parameter | Index biopsy | Any biopsy |
| Light microscopy pattern | ||
| No hypercellularity | 3 (19) | 3 (19) |
| Mesangial proliferative GN only | 2 (13) | 3 (19) |
| Endocapillary proliferative GN only | 5 (31) | 5 (31) |
| Mesangial and endocapillary proliferative GN | 4 (25) | 4 (25) |
| Membranoproliferative GN | 5 (31) | 10 (63) |
| Exudative features | 4 (25) | 4 (25) |
| Active crescents | 3 (19) | 5 (31) |
| Segmental glomerular scars | 5 (31) | 9 (56) |
| Concurrent biopsy findings | ||
| Cellular rejection | 6 (38) | 8 (50) |
| Antibody mediated rejection | 2 (13) | 4 (25) |
| Thrombotic microangiopathy | 1 (6) | 3 (19) |
| Acute/chronic CNI toxicity | 2 (13) | 5 (31) |
| Arterio/arteriolosclerosis | 4 (25) | 4 (25) |
| BK virus nephropathy | 1 (6) | 1 (6) |
| Acute tubular injury | 2 (13) | 4 (25) |
| None | 3 (19) | 3 (19) |
| Immunofluorescence findings | ||
| C3 only | 7 (44) | 9 (56) |
| C3 dominant | 9 (56) | 9 (56) |
| Non-C3 dominant GN | 1 (6) | 1 (6) |
| Electron microscopy findings | ||
| Mesangial deposits | 12 (75) | 13 (81) |
| Subendothelial deposits | 7 (44) | 9 (56) |
| Subepithelial | 7 (44) | 10 (63) |
| Intra-membranous deposits | 12 (75) | 13 (81) |
| Tubular basement membrane deposits | 7 (44) | 7 (44) |
| Subepithelial “hump-like” deposits | 5 (31) | 7 (44) |
- Citation: Zuckerman J, Pham PT, Parakkal M, Velazquez AF, Sarkar M, Pablos MA, Bunnapradist S, Lum EL. C3 glomerulopathy post kidney transplantation: A single center experience. World J Transplant 2025; 15(2): 101517
- URL: https://www.wjgnet.com/2220-3230/full/v15/i2/101517.htm
- DOI: https://dx.doi.org/10.5500/wjt.v15.i2.101517