King's College criteria and the Clichy-Villejuif criteria require adjustments for assessing acute liver failure due to yellow fever

Figure 1 Yellow fever is typically described as a biphasic disease. The initial phase is the viremia phase, which is characterized by the presence of the virus in the bloodstream and associated symptoms. Following this phase, there is a remission phase which is characterized by temporary symptom improvement. Only approximately 15% of patients progress to the toxic phase, which is characterized by severe symptoms and potential complications. The transitions between these phases reflect the progression and severity of the disease. AST: Aspartate aminotransferase; ALT: Alanine aminotransferase.