Prostaglandin E1 administration post liver transplantation and renal outcomes: A retrospective single center experience

Table 2 Postoperative outcomes

Variable	PGE1 (n = 44)	Non-PGE1 (n = 101)	P value
Intensive care unit length of stay (days)	8.1 ± 11.8	3.8 ± 4.6	0.003
Post-operative complication within 48 hours1	18.6	4.9	0.04
EGFR day 1 (mL/minute/1.73 m2)	52.6 ± 27.6	53.6 ± 29.8	0.86
AST day 1 (U/L)	1961.9 ± 1862.3	878 ± 741.4	0.0000
ALT day 1 (U/L)	1070.6 ± 895	547.7 ± 410	0.0000
Total bilirubin day 1 (mg/dL)	5.3 ± 3.3	4.6 ± 3.2	0.19
International normalized ratio day 1	2 ± 0.74	1.8 ± 0.4	0.03
EGFR day 7 (mL/minute)	46.3 ± 26.7	62.5 ± 34	0.009
AST day 7 (U/L)	82.3 ± 105.1	60.2 ± 111.5	0.27
ALT day 7 (U/L)	214 ± 122.6	146.7 ± 164.1	0.02
Total bilirubin day 7	3.1 ± 2.8	2 ± 1.7	0.002
Renal replacement therapy required	13.6	5.9	0.09
Dialysis (number of sessions)	0.91	0.27	0.13

¹Hepatic artery thrombosis, biliary complications, acute rejection, and cardiomyopathy; bilirubin normal range 03-1.2 mg/dL; international normalized ratio normal range: 0.8-1.2.

AST: Aspartate aminotransferase (normal range: 0-34 U/L); ALT: Alanine aminotransferase (normal range: 0-34 U/L); EGFR: Glomerular filtration rate (normal range: 60-200 mL/minute/1.73 m²); PGE1: Prostaglandin E1.