Genitourinary tumors and liver transplantation: A comprehensive review

Table 1 Possible proposal of acceptable liver donors with history of or current genitourinary malignancy (adapted from[15])

Minimal risk	Low to intermediate risk	High risk	Unacceptable risk
Current
NMIBC – in situ and T1	Prostate cancer-Gleason score 7	Prostate cancer- Gleason score >7	Metastatic prostate cancer
Prostate cancer - Gleason score ≤ 6	RCC 1-4 cm and Fuhrman grade I/II	RCC > 7 cm and Fuhrman grade III/IV	RCC stages T3/T4
RCC < 1 cm and Fuhrman grade I/II	RCC 4-7 cm and Fuhrman grade I/II		MIBC – post chemoradiation
History
Prostate cancer Gleason up to 6 Prostate cancer Gleason = 7 after curative treatment and cancer-free period > 5 yr	RCC 1-4 cm, FG I/II; RCC 4-7 cm, FG I/II	Prostate cancer with extraprostatic spread	Any metastatic genitourinary malignancy
RCC < 1 cm and FG I/II		RCC > 7 cm and FG III/IV	RCC stages T3/T4

RCC: Renal cell carcinoma; NMIBC: Nonmuscle-invasive bladder cancer; MIBC: Muscle-invasive bladder cancer; FG Fuhrman grade.