Liver transplantation for hepatocellular carcinoma in India: Are we ready for 2040?

Table 2 Indications of transarterial chemoembolization, transarterial radioembolization and stereotactic body radiotherapy in hepatocellular carcinoma–chronic liver disease patients awaiting liver transplantation

Modality	TACE	TARE	SBRT
Indications (No. Of centers preferred)	HCC patients on waitlist[12]	PVTT[12]	Vp1-3 PVTT[12]
	> Milan[4]	Large/multiple HCC[6]	Vp2 PVTT[2]
	> UCSF[2]	All affordable cases[3]	TACE/TARE not possible[4]
	Large tumor size[13]		Exophytic HCC[1]
	Awaiting donor fitness/logistical delay in transplant[2]		Diaphragm involved or local infiltration[1]
	High AFP[5]		Presence of shunt[1]
	Absence of PVTT[2]		Not preferred[3]
	TARE unaffordable/unavailable[4]

There is overlap among the respondents for the indications of either modalities. HCC: Hepatocellular carcinoma; PVTT: Portal vein tumor thrombosis; UCSF: University of California, San Francisco criteria; TACE: Trans-arterial chemo embolization; TARE: Trans-arterial radio embolization; SBRT: Stereotactic body radiotherapy; AFP: Alpha fetoprotein.