Reasons and effects of the decline of willing related potential living kidney donors

Table 5 Characteristics of potential living donors presented as total (n = 257) and as a comparison between the candidate (n = 74) and non-candidate (n = 183) groups of donors

Characteristics	Total PLDs, n = 257	Candidate PLDs, n = 74	Non-candidate PLDs, n = 183	P value
	mean ± SD (range)/number (%)
Mean age in yr	40.5 ± 10.4 (18-65)	41.0 ± 10.5 (21-60)	40.4 ± 10.5 (18-65)	0.498
Sex
Female	169 (65.8%)	49 (66.2%)	120 (65.6%)	> 0.999
Male	88 (34.2%)	25 (33.8%)	63 (34.4%)
Form of relatedness1
Aunt	4 (1.6%)	4 (5.4%)	0 (0%)	0.286
Brother	51 (19.8%)	14 (18.9%)	37 (20.2%)
Cousin	4 (1.6%)	0 (0%)	4 (2.2%)
Daughter	4 (1.6%)	1 (1.4%)	3 (1.6%)
Father	23 (8.9%)	7 (9.5%)	16 (8.7%)
Husband	6 (2.3%)	2 (2.7%)	4 (2.2%)
Mother	76 (29.6%)	23 (31.1%)	53 (29%)
Nephew	1 (0.4%)	0 (0%)	1 (0.6%)
Sister	53 (20.6%)	13 (17.6%)	40 (21.9%)
Son	4 (1.6%)	1 (1.4%)	3 (1.6%)
Uncle	1 (0.4%)	1 (1.4%)	0 (0%)
Wife	30 (11.7%)	8 (10.8%)	22 (12.0%)
Degree of relatedness
First	143 (55.6%)	42 (56.8%)	101 (55.2%)	0.020
Second	104 (40.5%)	27 (36.5%)	77 (42.1%)
Third	6 (2.3%)	5 (6.8%)	1 (0.6%)
Fourth	4 (1.6%)	0 (0%)	4 (2.2%)
Extent of evaluation
Complete	109 (42.4%)	74 (100.0%)	35 (19.1%)	NA
Incomplete	148 (57.6%)	0 (0%)	148 (80.9%)
Fate of PLDs
Donated	58 (22.6%)	58 (78.4%)	0 (0%)	NA
Excluded	144 (56.0%)	0 (0%)	144 (78.7%)	NA
Regressed2	18 (7.0%)	5 (6.8%)	13 (31.6%)
During evaluation	13 (72.2%)	0 (0%)	13 (100.0%)	NA
After evaluation	5 (27.8%)	5 (100%)	0 (0%)
Released	37 (14.4%)	11 (14.9%)	26 (68.4%)
Causes of donor release
Patient death	4 (10.8%)	3 (27.3%)	1 (3.9%)	0.186
Patient regression	22 (59.5%)	6 (54.5%)	16 (61.5%)
Patient non-candidacy	11 (29.7%)	2 (18.2%)	9 (34.6%)
Timing of PLDs release
During evaluation	26 (70.3%)	0 (0%)	26 (100.0%)	NA
After evaluation	11 (29.7%)	11 (100.0%)	0 (0%)
Time spent in PLDs evaluation in mo	2.2 ± 1.5 (0.5-6.0)	4.0 ± 0.9 (1-6)	1.5 ± 1.2 (0.5-5.0)	< 0.001

¹Among the 6 husband and 30 wife potential living donors (PLDs), only 13 of them were genetically related PLDs to their intended recipients (due to consanguineous marriage);

²The reason of regression was the fear of health drawbacks from donation in all PLDs. NA: Not available; PLD: Potential living donor; SD: Standard deviation.