Mortality assessment for pancreas transplants in the United States over the decade 2008-2018

Table 1 Demographic and clinical characteristics of patients listed for a pancreas transplant by transplant status and transplant type (May 31, 2008–May 31, 2018)

	SPK			PAK			PTA
	Transplant (n = 5834)	Waitlist (n = 3664)	P value	Transplant (n = 430)	Waitlist (n = 681)	P value	Transplant (n = 619)	Waitlist (n = 320)	P value
Age at registration (yr)			< 0.001			0.04			0.68
mean (SD)	40.1 (8.7)	41.0 (9.3)		40.6 (8.9)	41.8 (9.5)		41.7 (10.6)	41.4 (10.8)
Range	18.0 - 69.0	18.0 - 73.0		22.0 - 67.0	18.0 - 66.0		18.0 - 68.0	20.0 - 70.0
Gender			< 0.001			0.026			0.49
Female	2284 (39.1%)	1663 (45.4%)		174 (40.5%)	322 (47.3%)		378 (61.1%)	188 (58.8%)
Male	3550 (60.9%)	2001 (54.6%)		256 (59.5%)	359 (52.7%)		241 (38.9%)	132 (41.2%)
Race			0.3			0.08			< 0.001
White	3732 (64.0%)	2295 (62.6%)		336 (78.1%)	502 (73.7%)		567 (91.6%)	263 (82.2%)
Black	1229 (21.1%)	781 (21.3%)		37 (8.6%)	88 (12.9%)		25 (4.0%)	27 (8.4%)
Other	873 (15.0%)	588 (16.0%)		57 (13.3%)	91 (13.4%)		27 (4.4%)	30 (9.4%)
Ethnicity			0.22			0.7			0.012
Hispanic/Latino	714 (12.2%)	480 (13.1%)		46 (10.7%)	78 (11.5%)		23 (3.7%)	24 (7.5%)
Non-Hispanic/Non-Latino	5120 (87.8%)	3184 (86.9%)		384 (89.3%)	603 (88.5%)		596 (96.3%)	296 (92.5%)
Karnofsky score at registration			0.34			0.46			0.013
High	3441 (60.7%)	2151 (61.9%)		291 (70.3%)	427 (66.6%)		392 (64.9%)	229 (74.1%)
Middle	2108 (37.2%)	1259 (36.3%)		114 (27.5%)	199 (31.0%)		195 (32.3%)	76 (24.6%)
Low	121 (2.1%)	63 (1.8%)		9 (2.2%)	15 (2.3%)		17 (2.8%)	4 (1.3%)
BMI at registration			< 0.001			0.038			0.82
Normal	2847 (49.1%)	1640 (45.2%)		200 (46.9%)	287 (42.5%)		240 (40.1%)	133 (41.8%)
Underweight	95 (1.6%)	60 (1.7%)		5 (1.2%)	8 (1.2%)		11 (1.8%)	4 (1.3%)
Overweight	2180 (37.6%)	1311 (36.2%)		172 (40.4%)	259 (38.4%)		231 (38.6%)	116 (36.5%)
Obese	674 (11.6%)	615 (17.0%)		49 (11.5%)	121 (17.9%)		117 (19.5%)	65 (20.4%)
Duration of diabetes (yr)			0.064			0.052			0.28
mean (SD)	26.3 (9.0)	26.6 (9.2)		26.9 (8.6)	28.0 (9.5)		26.6 (11.4)	25.8 (11.7)
Range	0.0 - 59.0	0.0 - 60.0		3.0 - 49.0	2.0 - 55.0		0.0 - 58.0	1.0 - 57.0
Peripheral vascular disease at registration			< 0.001			0.96			0.78
No	5253 (91.5%)	3136 (87.4%)		384 (91.0%)	613 (91.1%)		545 (89.1%)	286 (89.7%)
Yes	488 (8.5%)	453 (12.6%)		38 (9.0%)	60 (8.9%)		67 (10.9%)	33 (10.3%)
Time on waitlist (yr)			< 0.001			< 0.001			< 0.001
mean (SD)	0.9 (1.0)	1.8 (1.7)		1.2 (1.1)	2.5 (2.0)		0.6 (0.8)	1.9 (1.9)
Range	0.0 - 7.4	0.0 - 10.3		0.0 - 5.9	0.0 - 9.9		0.0 - 6.7	0.0 - 10.0
Follow-up time after transplant (yr)
mean (SD)	3.7 (2.5)	NA		3.4 (2.6)	NA		3.3 (2.5)	NA
Range	0.0 - 10.1	NA		0.0 - 9.1	NA		0.0 - 9.1	NA

Continuous variables are presented as the mean and standard deviation (SD), and categorical variables are presented as frequency and percentage. SPK: Simultaneous pancreas-kidney; PAK: Pancreas after kidney; PTA: Pancreas transplant alone; NA: Not available.