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©The Author(s) 2023.
World J Transplant. Mar 18, 2023; 13(3): 58-85
Published online Mar 18, 2023. doi: 10.5500/wjt.v13.i3.58
Published online Mar 18, 2023. doi: 10.5500/wjt.v13.i3.58
Table 5 Differences between the ex-vivo lung perfusion protocols
| Description | Lund | OCS | Toronto |
| Year | 2001[176] | 2011[222] | 2008[177] |
| Perfusion parameters | |||
| Perfusate | CellularSteen solution + RBCs | CellularOCS proprietary solution + RBCs | AcellularSteen solution |
| Target haematocrit | 14% | 15%-25% | N/A |
| Target flow | 100% cardiac output | 2.0-2.5 L/min | 40% cardiac output |
| PA pressure | ≤ 20 mmHg | ≤ 20 mmHg | Flow dictated (usually < 15 mmHg) |
| Left atrium | Open | Open | Closed |
| Flow type | Continuous | Pulsatile | Continuous |
| Ventilation | |||
| Initial temperature | 32 oC | 34 oC | 32 oC |
| Tidal volume | 5-7 mL/kg | 6 mL/kg | 7 mL/kg |
| Respiratory rate | 20/min | 10/min | 7/min |
| FiO2 | 50% | 12% | 21% |
| PEEP | 5 cmH2O | 5-7 cmH2O | 5 cmH2O |
- Citation: Avtaar Singh SS, Das De S, Al-Adhami A, Singh R, Hopkins PM, Curry PA. Primary graft dysfunction following lung transplantation: From pathogenesis to future frontiers. World J Transplant 2023; 13(3): 58-85
- URL: https://www.wjgnet.com/2220-3230/full/v13/i3/58.htm
- DOI: https://dx.doi.org/10.5500/wjt.v13.i3.58