Outcomes of total pancreatectomy with islet autotransplantation: A systematic review and meta-analysis

Table 1 Risk of Bias assessment for cohort studies using the Newcastle Ottawa Scale

Ref.	Publish year	Study design	Q11	Q22	Q33	Q44	Q55	Q66	Q77	Q88	Total
Adult cohorts
Argo et al[39]	2008	Cohort, R	*		*	*		*	*	*	******(6)
Najarian et al[30]	1980	Cohort, R	*	*	*	*			*	*	******(6)
White et al[31]	2001	Cohort, P	*	*	*	*	*	*	*	*	********(8)
Mokadem et al[32]	2016	Cohort, R	*	*	*	*		*	*		******(6)
Garcae et al[24]	2013	Cohort, P	*	*	*	*		*	*	*	*******(7)
Gruessner et al[33]	2014	Cohort, P	*		*	*		*	*	*	******(6)
Wilson et al[15]	2014	Cohort, R	*		*	*		*	*	*	******(6)
Sutherland et al[16]	2012	Cohort, R	*		*	*		*	*	*	******(6)
Colling et al[35]	2017	Cohort, R	*	*	*	*	**	*	*	*	*********(9)
Ahmad et al[29]	2005	Cohort, R	*		*	*		*	*	*	******(6)
Solomina et al[25]	2017	Cohort, R	*		*	*		*	*	*	******(6)
Wang et al[36]	2013	Cohort, R	*		*	*		*	*	*	*******(7)
Bellin et al[18]	2016	Cohort, P	*		*	*		*	*	*	******(6)
Rabkin et al[37]	1999	Cohort, R	*		*	*		*	*	*	******(6)
Valente et al[41]	1985	Cohort, R	*		*	*		*	*	*	******(6)
Wahoff et al[50]	1995	Cohort, R	*		*	*		*	*	*	******(6)
Garcea et al[51]	2009	Cohort, P	*	*	*	*		*	*	*	*******(7)
Pediatric cohorts
Sutton et al[44]	2010	Cohort, R	*		*	*		*	*	*	******(6)
Chinnakotla et al[17]	2014	Cohort, R	*		*	*		*	*	*	******(6)
Bellin et al[18]	2016	Cohort, R	*	*	*	*		*	*	*	*******(7)
Bellin et al[52]	2010	Cohort, R	*		*	*		*	*		*****(5)

¹Representativeness of the exposed cohort.

²Selection of the non-exposed cohort.

³Ascertainment of exposure.

⁴Demonstration that outcome of interest was not present at the beginning of the study.

⁵Cohort comparability based on design.

⁶Assessment of outcome.

⁷Was follow-up long enough for outcomes to occur.

⁸Follow-up adequacy in terms of completeness.

R: Retrospective; P: Prospective; Q: Question.