Trends and outcomes of liver transplantation among older recipients in the United States

Table 1 Baseline characteristics of the study population comparing age young group (age 18-64) vs older group (age ≥ 65 years)

	Young group, age 18-64 (n = 135758)	Older group, age ≥ 65 (n = 20000)	P value
Age (IQR)	52 (45-58)	67 (66-69)	< 0.001
Female, n (%)	47934 (35.3)	7612 (38.1)	< 0.001
Race, %			< 0.001
White	73.5	75.5
Black	8.9	6.0
Hispanic/Latino	12.5	12.1
Asian	3.8	5.4
Others	1.3	0.9
BMI (IQR)	27.4 (24.0-31.7)	27.7 (24.5-31.5)	0.571
HCV, %	44876 (33.1)	5236 (26.2)	< 0.001
Diabetes, n (%)	226584 (22.3)	6784 (35.7)	< 0.001
L1-MELD	18 (12-26)	15 (10-22)	< 0.001
R2-MELD	21 (14-30)	18 (12-26)	< 0.001
Primary disease, %
Alcohol cirrhosis	22.3	15.3	< 0.001
HCV cirrhosis	25.2	19.0	< 0.001
NASH	5.9	16.4	< 0.001
HCC	6.9	14.9	< 0.001
Acute liver failure	5.2	2.5	< 0.001
Acute alcoholic hepatitis	0.35	0.13	< 0.001
Previous surgery, n (%)	48407 (35.7)	8899 (44.5)	< 0.001
SBP, n (%)	9147 (6.7)	1084 (5.4)	< 0.001
TIPSS, n (%)	7231 (5.3)	1187 (5.9)	0.001
Portal vein thrombosis, n (%)	4875 (3.6)	1162 (5.8)	< 0.001
Mechanical ventilation, n (%)	10464 (7.6)	888 (4.3)	< 0.001
Dialysis, n (%)	14284 (10.5)	2059 (10.3)	0.167
Wait days, d (IQR)	82 (16-263)	118 (27-310)	< 0.001
Re-transplant, n (%)	10125 (7.5)	727 (3.6)	< 0.001

¹Listing.

²Most recent.

IQR: Interquartile; BMI: Body mass index; HCV: Hepatitis C virus; NASH: Non-alcohol steatohepatitis; HCC: Hepatocellular carcinoma; SBP: Spontaneous bacterial peritonitis; TIPSS: Trans-jugular intrahepatic portosystemic shunt; MELD: Model for end-stage liver disease.