Simultaneous nephrectomy during kidney transplantation for polycystic kidney disease does not detrimentally impact comorbidity and graft survival

Table 1 Donor and recipient characteristics of 154 kidney transplant recipients suffering from autosomal dominant polycystic kidney with or without associated ipsilateral nephrectomy during isolated kidney transplantation in a single center transplant program from January 2007 until January 2019

	KT alone group (n = 77)	KT with associated ipsilateral nephrectomy (n = 77)	P value
Donor characteristics
Age, yr	46.23 ± 14.94	47.40 ± 14.86	NS
Gender, male/female, n (%)	42/35 (54.5/45.5)	37/40 (48.1/51.9)	NS
CMV status, negative/positive, n (%)	32/43 (55.2/47.8)	26/47 (35.6/64.4)	NS
Type of donor, living/deceased donor, n (%)	6/71 (7.8/92.2)	21/56 (27.3/72.7)	a
Type of deceased donor, DBD/DCD, n (%)	54/17 (76.1/23.9)	38/18 (67.9/32.1)	NS
Recipient characteristics
Age, yr	57.40 ± 9.89	53.40 ± 9.12	NS
Gender, male/female, n (%)	48/29 (62.3/37.7)	47/30 (61.0/38.9)	NS
Body mass index, kg/m²	25.69 ± 4.00	25.33 ± 3.76	NS
Blood group, n (%)			NS
A	33 (42.9)	42 (54.5)	NS
B	5 (6.5)	4 (5.2)	NS
AB	0 (0)	3 (3.9)	NS
O	39 (50.6)	28 (36.4)	NS
Pretransplant dialysis versus preemptive kidney transplant, n (%)	65/12 (84.4/15.6)	55/22 (71.4/28.6)	NS
Residual urine diuresis before transplant, mL	1057.75 ± 852.84	1188.42 ± 818.65	NS
Rank of transplant			NS
First transplant, n (%)	73 (94.8)	76 (98.7)	NS
Second transplant, n (%)	3 (3.9)	1 (1.3)	NS
Third transplant, n (%)	1 (1.3)	0 (0)	NS
Time on dialysis before transplantation, d	1105 ± 1198	720 ± 757	NS
HLA Mismatching (MM), n (%)			NS
0 MM	11 (14.3)	6 (7.8)
1 MM	8 (10.4)	7 (9.1)
2 MM	30 (39.0)	16 (30.8)
3 MM	23 (29.9)	30 (39)
4 MM	2 (2.6)	7 (9.1)
5 MM	3 (3.9)	6 (7.8)
6 MM	0 (0.0)	5 (6.5)
Hemoglobin before transplantation, g/dL	12.47 ± 1.72	12.69 ± 1.18	NS
Albumin before transplantation, g/dL	4.32 ± 0.40	4.24 ± 0.41	NS
Peritransplant plasmapheresis treatment, n (%)	14 (18)	3 (4)	a

^aP < 0.05. Data are given as the mean ± SD. ADPKD: Autosomal dominant polycystic kidney disease; CMV: Cytomegalovirus; DBD: Donation after brain death; DCD: Donation after circulatory death; HLA: Human leukocyte antigen; KT: Kidney transplantation; MM: Mismatching; NS: No significance.