Hemodynamic management in brain dead donors

Table 2 Vasoactive drugs and hormonal therapy in brain death donors–proposed regimen

	Dosage	Comments
Vasoactive
Norepinephrine (mcg/kg/min)	≤ 0.2 mcg/kg/min, if higher dosage needed add vasopressin	In potential heart donors, the lowest dosage is preferable
Vasopressin (U/h)	Up to 2.5 U/h
Hormonal replacement therapy
Idrocorticosteroid	100 mg bolus, 200 mg/24 h infusion
T3	4 mcg intravenous bolus, followed by infusion of 3 mcg per hour	T3 could be preferred since it is immediately available to tissues
Desmopressin (DDVAP)	4 mcg intravenous bolus eventually repeat every 6 to 8 h as needed

DDVAP: 1-deamino-8-D-arginine vasopressin.