Role of novel biomarkers in kidney transplantation

Table 11 Summary of biomarkers associated with post-transplant diabetes mellitus

Ref.	n	Sample	Biomarkers	Outcome	Study conclusion
Heldal et al[87], 2018	852	Plasma	20 biomarkers	PTDM	6/20 biomarkers associated with PTDM; significant include soluble TNF type 1a Pentraxin 3a macrophage migration inhibitory factora and endothelial protein C receptorb
Yepes-Calderón et al[88], 2019	516	Plasma	Malondialdehyde	PTDM	MDA was inversely associated with PTDM, independent of immunosuppressive therapy, transplant-specific covariates, lifestyle, inflammation, and metabolism parametersa (HR, 0.55; 95%CI, 0.36-0.83 per 1-SD increase)

^aP < 0.05 vs kidney transplant recipients without Post transplant diabetes mellitus.

^bP < 0.005 vs kidney transplant recipients without Post transplant diabetes mellitus. PTDM: Post transplant diabetes mellitus; TNF: Tumor necrosis factor; MDA: Malondialdehyde; HR: Hazard ratio; SD: Standard deviation; CI: Confidence interval.