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©The Author(s) 2020.
World J Transplant. May 29, 2020; 10(5): 90-103
Published online May 29, 2020. doi: 10.5500/wjt.v10.i5.90
Published online May 29, 2020. doi: 10.5500/wjt.v10.i5.90
Table 5 Tacrolimus doses and concentrations by ancestry in the first 6 mo posttransplant[40]
| Native American, n = 77 | Asian ancestry, n = 91 | European ancestry, n = 1966 | African American, n = 461 | P value | |
| Trough concentration (ng/mL) | 8.3 | 8.4 | 8.4 | 6.9 | < 0.0001 |
| Total daily dose (mg) | 5.0 | 6.0 | 5.0 | 8.0 | < 0.0001 |
| Dose-normalized trough concentration (ng/mL per total daily dose in mg) | 1.73 | 1.50 | 1.56 | 0.78 | 0.0001 |
- Citation: Salvadori M, Tsalouchos A. Pharmacogenetics of immunosuppressant drugs: A new aspect for individualized therapy. World J Transplant 2020; 10(5): 90-103
- URL: https://www.wjgnet.com/2220-3230/full/v10/i5/90.htm
- DOI: https://dx.doi.org/10.5500/wjt.v10.i5.90