Machine perfusion in abdominal organ transplantation: Current use in the Netherlands

Table 1 Outcomes from meta-analyses or large studies comparing donation after circulatory death to donation after brain death outcomes in abdominal organ transplantation

	DCD	DBD	P value
Kidney[56]
PNF (%)	3.2	2.6	0.06
DGF (%)	48.5	24.9	< 0.001a
1-yr eGFR1	47.4 (35.6-61.2)	48.7 (37.3-61.1)	0.69
5-yr graft survival (%)	76.8	78.1	0.60
5-yr patient survival (%)	86.5	89.4	< 0.001a
Liver[57]
Biliary complications (%)	26	16	< 0.001a
Ischemic cholangiopathy (%)	16	3	< 0.001a
3-yr graft survival (%)	73	74	0.01a
3-yr patient survival (%)	82	88	0.04a
Pancreas[7]
Graft survival	HR 0.98 (0.74-1.31)	Reference value	0.92
Patient survival	HR 1.31 (0.62-2.78)	Reference value	0.47
Graft thrombosis	OR 1.67 (1.04-2.67)	Reference value	0.006a

¹Data is presented as median and interquartile range.

^aStatistically significant. DBD: Donation after brain death; DCD: Donation after circulatory death; DGF: Delayed graft function; eGFR: Estimated glomerular filtration rate; HR: Hazard ratio; OR: Odds ratio; PNF: Primary non function.