What is the best biological treatment for rheumatoid arthritis? A systematic review of effectiveness

Table 3 Quality assessment of articles for Newcastle Ottawa scale

N study	Ref.	Selection				Comparability	Results			Total
		Representati-veness of the cases	Selection of controls	Ascertain-ment of exposure	Demonstration that outcome of interest was not present at start of study	Comparability of cohorts on the basis of the design or analysis	Assessment of outcome	Was follow-up long enough for outcomes to occur	Adequacy of follow up of cohorts
1	Geborek et al[12]	1	1	1	1	2	0	1 (12 mo)	1	8
2	Van Vollenhoven et al[13]	0	1	1	1	2	0	1 (24 mo)	0	6
3	Cohen et al[14]	1	1	1	1	1	0	1 (3 mo)	0	6
4	Finckh et al[15]	1	1	1	0	1	1	1 (12 mo)	1	7
5	Heiberg et al[16]	1	1	1	1	2	0	1 (6 mo)	1	8
6	Hyrich et al[17,18]	1	1	1	1	2	0	1 (6 mo)	1	8
7	Kristensen et al[19]	1	1	1	0	2	0	1 (36 mo)	0	6
8	Bernal Rivera et al[20]	1	1	1	0	2	0	1 (12 mo )	1	7
9	Fernández-Nebro et al[21]	1	1	1	1	2	0	1 (6 mo)	1	8
10	Radstake et al[23]	0	1	1	1	2	0	1 (6 mo)	0	6
11	Kievit et al[22]	1	1	1	1	2	0	1 (6 mo)	0	7
12	Bazzani et al[24]	1	1	1	0	2	1	1 (6 mo)	1	8
13	Greenwood et al[47]	0	1	1	1	2	0	1 (12 mo)	0	6
14	Laas et al[25]	1	1	1	1	2	1	1 (3 mo)	1	9
15	Arenere Mendoza et al[26]	1	1	1	1	2	0	1 (12 mo)	0	7
16	Buch et al[46]	1	1	1	0	2	0	1 (6 mo)	0	6
17	Canhão et al[27]	1	1	1	0	2	0	1 (12 mo)	1	7
18	Hetland et al[28]	1	1	1	1	2	0	1 (12 mo)	1	8
19	Blom et al[29]	1	1	1	1	2	1	1 (12 mo)	1	9
20	Chatzidionysiou et al[30]	1	1	1	1	2	0	1 (12 mo)	0	7
21	Gotenberg et al[45]	1	1	1	1	2	0	1 (6 mo)	1	8
22	Iannone et al[32]	1	1	1	0	2	0	1 (48 mo)	0	6
23	Leffers et al[33]	1	1	1	1	2	0	1 (12 mo)	0	7
24	Martínez-Pérez et al[44]	0	1	0	1	2	0	1 (12 mo)	0	5
25	Wakabayashi et al[34]	0	1	1	1	2	1	1 (12 mo)	1	8
26	Finckh et al[36]	1	1	1	1	1	1	1 (24 mo)	1	8
27	Gomez-Reino et al[35]	1	1	1	0	2	1	1 (12 mo)	1	8
28	Greenberg et al[37]	1	1	1	1	2	0	1 (24 mo)	1	8
29	Kekow et al[38]	1	1	1	1	2	0	1 (6 mo)	1	8
30	Schabert et al[39]	1	1	1	1	1	1	1 (12 mo)	1	8
31	Chatzidionysiou et al[40]	1	1	1	0	2	0	1 (6 mo)	0	6
32	Keystone et al[43]	0	1	1	0	2	0	1 (12 mo)	0	5
33	Emery et al[41]	1	1	1	0	2	0	1(12 mo)	0	6
34	Flouri et al[42]	1	1	1	1	2	0	1 (12 mo)	1	8
35	Harrold et al[31]	1	1	1	0	2	0	1 (12 mo)	0	6