Monitoring osteoporosis therapy: Can FRAX help assessing success or failure in achieving treatment goals?

Table 3 Correlation of the World Health Organization fracture risk assessment tool stratified major osteoporotic and hip fracture 10-year probability with the total proximal femur bone mineral density measurement

	BMD total proximal femur at baseline	BMD total proximal femur at 2-yr	BMD total proximal femur at 5-yr
FRAX 10-yr major osteoporosis fracture risk probability	-0.551b	-0.449b	-0.479b
FRAX 10-yr hip fracture risk probability	-0.741b	-0.547b	-0.584b
Change in FRAX 10-yr major osteoporosis fracture probability at 2-yr		-0.459b
Change in FRAX 10-yr hip fracture probability at 2-yr		-0.557b
Major osteoporosis fracture probability at 5-yr			-0.489b
Change in FRAX 10-yr hip fracture probability at 5-yr			-0.594b

^bP < 0.01, BMD total proximal femur at 2-yr and 5-yr vs BMD total proximal femur at baseline. BMD: Bone mineral density; FRAX: The World Health Organization fracture risk assessment tool.