Hot topics in lupus pregnancy

Table 5 Pregnancy morbidity of antiphospholipid syndrome

Classification criteria of APS in pregnancy

One or more unexplained deaths of a morphologically normal fetus at or beyond the 10th week of gestation, with normal fetal morphology documented by ultrasound or by direct examination of the fetus, or (b) One or more premature births of a morphologically normal neonate before the 34th week of gestation because of: (1) eclampsia or severe preeclampsia defined according to standard definitions[11], or (2) recognized features of placental insufficiency-, or (c) Three or more unexplained consecutive spontaneous abortions before the 10th week of gestation, with maternal anatomic or hormonal abnormalities and paternal and maternal chromosomal causes excluded.

Others obstetric manifestations of APS

Increased risks of intrauterine growth retardation

HELLP syndrome

Utero-placental insufficiency

Preeclampsia

Risk of thrombosis in the mother

APS: Antiphospholipid syndrome.