B cell depletion in scleroderma lung disease: A promising new treatment?

Table 1 All relevant studies have so far reported clinical and/or histologic improvement of skin fibrosis

Study	Participants (n)	Evaluation time point (mo)	Clinical assessment skin	Histologic improvement-skin	Lung function tests
Smith et al[9]	8	6	Improved	Yes	Stable
Lafyatis et al[8]	15	6/12	Stable	Yes	Stable
Bosello et al[10]	9	6-36	Improved	Not reported	Stable
Daoussis et al[11]	8	12	Improved	Yes	Improved