Lipoprotein based drug delivery: Potential for pediatric cancer applications

Table 1 Frequently encountered pediatric malignancies[19]

Type of cancer	Definition/characteristics	% Incidence 2005
Leukemia	Leukemia is cancer of the body's blood-forming tissues, including the bone marrow and the lymphatic system	34
Brain and central nervous system tumors	Normal cells in the brain or the spinal cord change and grow uncontrollably, forming a mass	23
Neuroblastoma	It is a neuroendocrine tumor, most frequently originating in one of the adrenal glands, in addition to nerve tissues in the neck, chest, abdomen, or pelvis	7
Wilm's tumor or nephroblastoma	Cancer of kidney that occurs in children	5
Lymphoma (Hodgkins and Non-Hodgkins)	Blood cell tumor that develops from lymphocytes	12
Rhabdomyosarcoma	Cancer of soft tissues where the cancer cells originate from skeletal muscle progenitor	3
Bone cancer	Osteosarcoma and Ewing's sarcoma are the most common malignancies of bone	4
Germ cell tumors	Germ cells tumors typically emerge from gonads but may also originate in other parts of the body, while arising from embryonic germ cell "rests"	N/A

N/A: Statistics not available.