Copyright
©2014 Baishideng Publishing Group Inc.
Figure 2 Telomeres an telomerase complex.
(TTAGG)n sequences form a 3’-overhang on the 3’ end of chromosome. Telomerase is composed by hTERT and hTER subunits; hTER is the RNA template for DNA synthesis to add new telomeric TTAGG sequences on 3’-overhang; B: DNA polymerase completes the lagging strand; C: GRN163L sequence complementary. hTERT: Human TElomerase Reverse Transcriptase; hTER: Human TElomerase RNA.
- Citation: Picariello L, Grappone C, Polvani S, Galli A. Telomerase activity: An attractive target for cancer therapeutics. World J Pharmacol 2014; 3(4): 86-96
- URL: https://www.wjgnet.com/2220-3192/full/v3/i4/86.htm
- DOI: https://dx.doi.org/10.5497/wjp.v3.i4.86