Review
Copyright ©2014 Baishideng Publishing Group Inc.
World J Pharmacol. Dec 9, 2014; 3(4): 86-96
Published online Dec 9, 2014. doi: 10.5497/wjp.v3.i4.86
Figure 2
Figure 2 Telomeres an telomerase complex. (TTAGG)n sequences form a 3’-overhang on the 3’ end of chromosome. Telomerase is composed by hTERT and hTER subunits; hTER is the RNA template for DNA synthesis to add new telomeric TTAGG sequences on 3’-overhang; B: DNA polymerase completes the lagging strand; C: GRN163L sequence complementary. hTERT: Human TElomerase Reverse Transcriptase; hTER: Human TElomerase RNA.