Association of serum bilirubin and non-alcoholic fatty liver disease: A feasible therapeutic avenue?

Table 1 Summary of characteristics of studies on the association of bilirubin with non-alcoholic fatty liver disease

Ref.	Study designTotal number of patients	Study population	Main outcome measure
Chang et al[32]	Cohort-longitudinal	Korean men from a single large semiconductor company (South Korea)	Conjugated bilirubin
	n = 5900
Kwak et al[33]	Cross-section	Health check-general
	n = 17348	Population (South Korea)	Total bilirubin
Duseja et al[34]	Prospective	Hospital setting unclear, probably Tertiary (India)	Unconjugated bilirubin
	n = 67
Hjelkrem et al[35]	Retrospective	Tertiary hospital patients undergoing liver biopsy (United States)	Unconjugated bilirubin
	n = 641
Kumar et al[36]	Cross-sectional	Tertiary hospital, outpatient NAFLD clinic (India)	Unconjugated bilirubin
	n = 204
Chisholm et al[37]	Cross-sectional	Liver biopsy prior to bariatric surgery (United States)	Total bilirubin
	n = 370
Tarantino et al[38]	Cross-sectional	Tertiary hospital, outpatient likely liver clinic (Italy)	Unconjugated bilirubin
	n = 186

NAFLD: Non-alcoholic fatty liver disease.