Drug-transporter interaction testing in drug discovery and development

doi:10.5497/wjp.v2.i1.35

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World Journal of Pharmacology

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2220-3192

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Pharmacol. Mar 9, 2013; 2(1): 35-46
Published online Mar 9, 2013. doi: 10.5497/wjp.v2.i1.35

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Figure 1 Expression of transporters in human enterocytes (A), brain microcapillary endothelial cells (B), hepatocytes (C) and renal proximal tubule epithelial cells (D). OCTN: Organic cation transporter novel; BCRP: Breast cancer resistance protein; MRP: Multidrug resistance associated protein; OATP: Organic anion transporting polypeptide; ENT: Equilibrative nucleoside transporter; PEPT: Peptide transporter; P-gp: P-glycoprotein; MATE: Multidrug and toxin extrusion protein; BSEP: Bile salt export pump.

Citation: Krajcsi P. Drug-transporter interaction testing in drug discovery and development. World J Pharmacol 2013; 2(1): 35-46
URL: https://www.wjgnet.com/2220-3192/full/v2/i1/35.htm
DOI: https://dx.doi.org/10.5497/wjp.v2.i1.35