Copyright
©2013 Baishideng.
World J Pharmacol. Mar 9, 2013; 2(1): 1-17
Published online Mar 9, 2013. doi: 10.5497/wjp.v2.i1.1
Published online Mar 9, 2013. doi: 10.5497/wjp.v2.i1.1
Parameters | GCV | (Biotin-GCV) | |
Biotin-GCV | Regenerated GCV | ||
AUC (mg/mL per minute) | 10.6 ± 1.27 | 17.5 ± 1.38a | 1.85 ± 0.744 |
λz (× 10-3/min) | 2.58 ± 0.124 | 3.19 ± 0.536 | |
T1/2 (min) | 270 ± 15.7 | 222 ± 40.5 | |
Vss (mL) | 1.56 ± 0.100 | 1.47 ± 0.106 | |
Cl (μL/min) | 4.39 ± 0.603 | 5.45 ± 0.673 | |
MRT last (min) | 197 ± 22.2 | 175 ± 17.6 | 264 ± 9.26 |
Clast (μg/mL) | 7.06 ± 1.38 | 8.28 ± 2.27 | |
Cmax (μg/mL) | 5.37 ± 0.435 | ||
Tmax (min) | 66.7 ± 23.1 |
- Citation: Boddu SH, Nesamony J. Utility of transporter/receptor(s) in drug delivery to the eye. World J Pharmacol 2013; 2(1): 1-17
- URL: https://www.wjgnet.com/2220-3192/full/v2/i1/1.htm
- DOI: https://dx.doi.org/10.5497/wjp.v2.i1.1