Gene regulatory networks in atrial fibrillation

Figure 2 Schematic representation genes associated to atrial fibrillation. On the one hand, gene mutations associated to atrial fibrillation (AF) are illustrated. On the other hand, genes associated to AF by means of GWAS are also illustrated. In the latter, three subset of genes are provided: (1) those directly linked to AF GWAS analyses; (2) those related to AF, but identified in arrhythomogenic syndromes GWAS analyses; and (3) risk variants association studies in small AF cohorts by a candidate approach strategy. Genes highlighted in bold represent those genes identified in AF by multiple approaches. GWAS: Genome-wide association analyses.