Preimplantation HLA typing: Practical tool for stem cell transplantation treatment of congenital disorders

Table 1 Experience in preimplantation genetic diagnosis with HLA typing

Disease	Patients	Cycles	No. of embryo transfers	No. embryos transferred	Pregnancy	Birth
Thalassemia/sickle cell disease	51	149	82	130	20	15
FANCA, FANCC, FANCD2, FANCF, FANCI, FANCJ	17	53	34	52	7	4
WAS	2	2	2	4	1	1
X-ALD	2	5	1	1	0	0
Hyper IgM	5	8	6	9	3	2
HED-ID	2	9	6	8	2	3
DBA	3	5	3	6	2	2
Krabbe	1	1	1	2	1	2
DM	1	2	1	2	1	2
Chronic granulomatous disease	1	3	3	5	1	1
Total	85	238	139	219	38	32

WAS: Wiscott-aldrich syndrome; X-ALD: X-linked adrenoleukodystrophy; HED-ID: Hypohidrotic ectodermal displasia with immune deficiency; DBA: Diamond-Blackfan anemia; DM: Dystrophia myotonica.