Genome-wide associations, polygenic risk, and Mendelian randomization reveal limited interactions between John Henryism and cynicism

Figure 2 Manhattan and quantile-quantile plots of genome-wide associations. A: Manhattan plot for cynical distrust score; B: Manhattan plot for high cynical distrust; C: QQ plot for cynical distrust score; D: QQ plot for high cynical distrust; E: Manhattan plot for cynicism score; F: Manhattan plot for high cynicism; G: QQ plot for cynicism score; H: QQ plot for high cynicism; I: Manhattan plot for John Henryism score; J: Manhattan plot for high John Henryism; K: QQ plot for John Henryism score; L: QQ plot for high John Henryism. Black dots = candidate associations from the training set (n = 1852); green dots = associations replicated in the verification set (n = 465); blue line = genome-wide suggestive association (P = 5 × 10^-6); red line = genome-wide significant association (P = 5 × 10^-8).