Role of chemokines and cytokines in the neuropathogenesis of African trypanosomiasis

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Nov 25, 2013 (publication date) through Dec 1, 2024

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World Journal of Clinical Infectious Diseases

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2220-3176

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Infect Dis. Nov 25, 2013; 3(4): 79-85
Published online Nov 25, 2013. doi: 10.5495/wjcid.v3.i4.79

Table 3 Selected cytokines and associated neurological and neuroendocrine features of African trypanosomiasis

Cytokine	Possible neurological and neuroendocrine features associated with	Ref.
IFN-γ	Sleep pattern disruptions, hyperalgesia/hyperesthesia and pain	[41,60]
IL1β	Hyperalgesia/ hyperesthesia and pain, neurodegeneration	[28,29,61]
IL-6	Hypopituitarism and endocrine dysfunctions, sleep pattern disruptions, hyperalgesia/ hyperesthesia and pain	[38]
TNF-α	Hypopituitarism and endocrine dysfunctions, sleep pattern disruptions, hyperalgesia/hyperesthesia and pain, neurodegeneration	[28,29,38,41]

IFN: Interferon; IL: Interleukin; TNF: Tumor necrosis factor.

Citation: Masocha W. Role of chemokines and cytokines in the neuropathogenesis of African trypanosomiasis. World J Clin Infect Dis 2013; 3(4): 79-85
URL: https://www.wjgnet.com/2220-3176/full/v3/i4/79.htm
DOI: https://dx.doi.org/10.5495/wjcid.v3.i4.79